2D MoS2 Nanosheets Induce Ferroptosis by Promoting NCOA4‐Dependent Ferritinophagy and Inhibiting Ferroportin (Small 24/2023)
Source abstract
Abstract
2D MoS2 Nanosheets MoS2 nanosheets accumulate Fe2+ in lysosomes by promoting NCOA4-dependent ferritinophagy. Fe2+ leaks from the damaged lysosomes into the cytoplasm, resulting in ferroptosis. This has important implications for elucidating the toxicity of 2D nanoparticles and determining their medical applications. More details can be found in article number 2208063 by Wei Jiang and co-workers.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Iron Metabolism and Disorders · Ferroptosis and cancer prognosis · MicroRNA in disease regulation
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Environment Research Institute Shandong University Qingdao 266237 P. R. China
Marine College Shandong University Weihai 264209 P. R. China
Department of Occupational and Environmental Health School of Public Health Qingdao University Qingdao 266071 P. R. China
School of Environmental Science and Engineering Shandong University Qingdao 266237 P. R. China
Stockbridge School of Agriculture University of Massachusetts Amherst MA 01003 USA
References
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