journal article·2022-07Open access

Spermine‐Responsive Intracellular Self‐Aggregation of Gold Nanocages for Enhanced Chemotherapy and Photothermal Therapy of Breast Cancer (Small 30/2022)

Beibei Xie, Huichao Zhao, Mingju Shui, Yuan‐Fu Ding, Chen Sun, Ziyi Wang, Cheng Gao, Guosong Chen, Ruibing Wang

Small· Volume 18· Issue 30

Abstract

Breast Cancer Therapy In article number 2201971, Ruibing Wang and co-workers develop supramolecular peptide (based upon the host–guest interaction between cucurbit[7]uril and Phe-Phe-Val-Leu-Lys) capped Au nanocages, to allow self-aggregation into micron-sized clusters inside spermine-overexpressed tumor cells, leading to specific accumulation and retention of Au nanocages in breast tumor for synergistic photothermal therapy and chemotherapy.
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Research context

OpenAlex topics: Supramolecular Self-Assembly in Materials · Nanoplatforms for cancer theranostics · Supramolecular Chemistry and Complexes

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Affiliations

State Key Laboratory of Quality Research in Chinese Medicine Institute of Chinese Medical Sciences University of Macau Taipa Macau SAR 999078 China

MoE Frontiers Science Center for Precision Oncology University of Macau Taipa Macau SAR 999078 China

State Key Laboratory of Molecular Engineering of Polymers Fudan University Shanghai China

References

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