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journal article·2021-09Open access

Automated Optical Tweezers Manipulation to Transfer Mitochondria from Fetal to Adult MSCs to Improve Antiaging Gene Expressions (Small 38/2021)

Adnan Shakoor, Bin Wang, Lei Fan, Lingchi Kong, Wendi Gao, Jiayu Sun, Kwan Man, Gang Li, Dong Sun

Small· Volume 17· Issue 38
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Source abstract

Abstract

Mitochondrial Transfer In article number 2103086, Gang Li, Dong Sun, and co-workers present a novel method of controlling the quality and quantity of mitochondria transferred to single cells using an automated optical tweezer-based micromanipulation system. The transfer of isolated mitochondria from fetal mesenchymal stem cells (fMSCs) to adult mesenchymal stem cells (aMSCs) by the developed system can significantly increase the anti-aging and metabolic gene expressions in the aMSCs.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Pluripotent Stem Cells Research · Mitochondrial Function and Pathology · Reproductive Biology and Fertility

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Affiliations

Department of Biomedical Engineering City University of Hong Kong Hong Kong 99907 China

The Chinese University of Hong Kong (CUHK) Guangzhou Regenerative Medicine and Health Guangdong Laboratory (GDL) Advanced Institute for Regenerative Medicine Bioland Laboratory (Guangzhou Regenerative Medicine and Health Guangdong Laboratory) Guangzhou 510530 China

Department of Orthopaedics and Traumatology Stem Cells and Regeneration Laboratory Li Ka Shing Institute of Health Sciences The Chinese University of Hong Kong 99907 Hong Kong S.A.R.

Department of Surgery The University of Hong Kong Hong Kong 99907 Hong Kong S.A.R.

References

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