DataVXSmallPaper
journal article·2021-07

Chemoimmunotherapy: Coordination and Redox Dual‐Responsive Mesoporous Organosilica Nanoparticles Amplify Immunogenic Cell Death for Cancer Chemoimmunotherapy (Small 26/2021)

Fan Zhang, Fangman Chen, Chao Yang, Lei Wang, Hanze Hu, Xuezhao Li, Xiao Zheng, Zheng Wang, Zhimin Chang, Tianyu Li, Li Li, Mingfeng Ge, Jinzhi Du, Wen Sun, Wen‐fei Dong, Dan Shao

Small· Volume 17· Issue 26
Publisher page
Source abstract

Abstract

In article number 2100006, Wen Sun, Wen-fei Dong, Dan Shao, and co-workers fabricate diselenide-bridged mesoporous organosilica nanoparticles for coordination and redox dual-responsive delivery of chemotherapeutic ruthenium compound KP1339. Such immunogenic cell death nano-amplifier performed robust suppression on primary and distant tumor growth, as well as pulmonary metastasis of breast cancer with low systematic toxicity when combined with anti-PD-L1.
Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Nanoplatforms for cancer theranostics

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Affiliations

School of Biomedical Engineering (Suzhou) Division of Life Sciences and Medicine University of Science and Technology of China Hefei 230026 China

CAS Key Laboratory of Bio Medical Diagnostics Suzhou Institute of Biomedical Engineering and Technology Chinese Academy of Sciences Suzhou 215163 China

School of Biomedical Sciences and Engineering National Engineering Research Center for Tissue Restoration and Reconstruction South China University of Technology Guangzhou Guangdong 510630 China

Department of Biomedical Engineering Columbia University New York NY 10027 USA

State Key Laboratory of Fine Chemicals School of Chemical Engineering Dalian University of Technology Dalian 116024 China

Institutes for Life Sciences School of Medicine South China University of Technology Guangzhou International Campus Guangzhou Guangdong 510006 China

References

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