journal article·2017-08Open access

Cancer Therapy: TPGS‐Functionalized Polydopamine‐Modified Mesoporous Silica as Drug Nanocarriers for Enhanced Lung Cancer Chemotherapy against Multidrug Resistance (Small 29/2017)

Wei Cheng, Chaoyu Liang, Lv Xu, Gan Liu, Nansha Gao, Wei Tao, Lingyan Luo, Yixiong Zuo, Xusheng Wang, Xudong Zhang, Xiaowei Zeng, Lin Mei

Small· Volume 13· Issue 29

Abstract

In article number 1700623, by Xiaowei Zeng, Lin Mei, and co-workers, a pH-sensitive drug delivery vehicle based on TPGS-modified polydopamine-coated mesoporous silica nanoparticles is developed. This nanoparticle shows good performance inhibiting cancer multidrug resistance by suppressing the function of the P-glycoprotein. This drug-loaded delivery platform exhibits significantly superior antitumor efficacy.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Nanoparticle-Based Drug Delivery · Metal-Organic Frameworks: Synthesis and Applications · Nanoplatforms for cancer theranostics

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Division of Life and Health Sciences Graduate School at Shenzhen Tsinghua University Shenzhen 518055 China

Department of Chemistry Tsinghua University Beijing 100084 China

School of Pharmaceutical Sciences (Shenzhen) Sun Yat‐sen University Guangzhou 510275 P. R. China

College of Optoelectronic Engineering Shenzhen University Shenzhen 518060 China

References

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