DataVXSmallPaper
journal article·2016-08

Cancer Treatment: Superporous Poly(ethylene glycol) Diacrylate Cryogel with a Defined Elastic Modulus for Prostate Cancer Cell Research (Small 29/2016)

Bettina Göppert, Thomas Sollich, Paul Abaffy, Angelica Cecilia, Jan Heckmann, Antje Neeb, Anne Bäcker, Tilo Baumbach, Friederike J. Gruhl, Andrew C. B. Cato

Small· Volume 12· Issue 29
Publisher page
Source abstract

Abstract

On page 3985, F. J. Gruhl, A. C. B. Cato engineer superporous poly(ethylene glycol) diacrylate cryogels that mimic the stiffness of malignant prostate tissues for studies of prostate cancer cell growth and function. Cells grow in an anchorage-dependent manner in this scaffold for three weeks and respond to androgen and antiandrogen treatment. Compared to 2D cell culture system, androgen-dependent prostate target gene expression is highly regulated in this system.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Cancer, Hypoxia, and Metabolism · Nanoparticle-Based Drug Delivery · Nanoplatforms for cancer theranostics

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Karlsruhe Institute of Technology Institute of Microstructure Technology Hermann‐von‐Helmholtz‐Platz 1 76344 Eggenstein‐Leopoldshafen Germany

Karlsruhe Institute of Technology Institute of Functional Interfaces Hermann‐von‐Helmholtz‐Platz 1 76344 Eggenstein‐Leopoldshafen Germany

Karlsruhe Institute of Technology Institute of Beam Physics and Technology Hermann‐von‐Helmholtz‐Platz 1 76344 Eggenstein‐Leopoldshafen Germany

Karlsruhe Institute of Technology Institute of Toxicology and Genetics Hermann‐von‐Helmholtz‐Platz 1 76344 Eggenstein‐Leopoldshafen Germany

Karlsruhe Institute of Technology Institute of Photon and Synchrotron Radiation Hermann‐von‐Helmholtz‐Platz 1 76344 Eggenstein‐Leopoldshafen Germany

References

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