journal article·2014-09Open access

Reactive Oxygen Species: Rhodamine‐Modified Upconversion Nanophosphors for Ratiometric Detection of Hypochlorous Acid in Aqueous Solution and Living Cells (Small 17/2014)

Yi Zhou, Wenbo Pei, Chenyuan Wang, Jixin Zhu, Jiansheng Wu, Qinyu Yan, Ling Huang, Wei Huang, Cheng Yao, Joachim Say Chye Loo, Qichun Zhang

Small· Volume 10· Issue 17

Abstract

Hypochlorous acid (HOCl), a reactive oxygen species (ROS) produced by myeloperoxidase (MPO) enzyme-mediated peroxidation of chloride ions, acts as a critical microbicidal agent in response to inflammatory stimuli. As reported by J. S. C. Loo, Q. C. Zhang, and co-workers on page 3560, a water-soluble nano detection system using rhodaminemodified upconversion nanophosphor is developed for ratiometric UCL imaging of HOCl in living cells, which could provide a novel next-generation imaging technique for bio-imaging HOCl in living systems without background noise.
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Research context

OpenAlex topics: Molecular Sensors and Ion Detection · Analytical Chemistry and Sensors · bioluminescence and chemiluminescence research

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Affiliations

School of Materials Science and Engineering Nanyang Technological University Singapore 639798 Singapore

School of Chemical and Biomedical Engineering Nanyang Technological University 637457 Singapore

Institute of Advanced Materials Nanjing Technological University Nanjing 210009 China

College of Science Nanjing Technological University Nanjing 211816 China

References

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