journal article·2014-08Open access

Gene Organization: Nano‐Dissection and Sequencing of DNA at Single Sub‐Nuclear Structures (Small 16/2014)

Brandon K. Chen, David Anchel, Zheng Gong, Rachel Cotton, Ren Li, Yu Sun, David P Bazett‐Jones

Small· Volume 10· Issue 16

Abstract

A technique for extracting DNA from a cell nucleus is reported by Y. Sun, D. P. Bazett-Jones, and co-workers. The nano-dissection tool is shown above the specimen in a scanning electron microscope image before and after DNA extraction. On page 3267, extracted DNA is then identified by sequencing. Regions of interest identified by fluorescence microscopy are determined by correlative imaging and are precisely manipulated.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Genetics, Bioinformatics, and Biomedical Research · Molecular Biology Techniques and Applications · Advanced biosensing and bioanalysis techniques

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Affiliations

Department of Mechanical Engineering University of Toronto M5S 3G8

Genetics and Genome Biology Program The Hospital for Sick Children M5G 1×8

References

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