Dual Biosignal‐Functional Injectable Microspheres for Remodeling Osteogenic Microenvironment (Small 36/2022)
Source abstract
Abstract
Bone Defect Treatment Inspired by the concept of macrophage reprogramming, Wenguo Cui, Youcheng Yu, and co-workers construct immuno-engineering porous microspheres (IL-4/loaded liposomes (Ls)/poly (l-lactic acid) (PLLA)) to realize bone repair through the “physical” porous structure and “molecular” IL-4 chemokines dual signal regulation. The immuno-reprogramming IL-4/Ls/PLLA microspheres achieve the precise immuno-reprogramming of macrophages by driving the activation of the signaling pathways. This immune reengineering strategy paves the way for clinical bone defect treatment.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Mesenchymal stem cell research · Bone Tissue Engineering Materials
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Stomatology Zhongshan hospital Fudan University No. 180 Fenglin road Shanghai 200032 China
Department of Orthopaedics Shanghai Key Laboratory for Prevention and Treatment of Bone and Joint Diseases Shanghai Institute of Traumatology and Orthopaedics Ruijin Hospital, Shanghai Jiao Tong University School of Medicine 197 Ruijin 2nd Road Shanghai 200025 P. R. China
Department of Stomatology Xuhui Central Hospital 996 Huaihaizhong Road Shanghai 200031 P. R. China
References
Reference metadata was not supplied for this record.