journal article·2019-03Open access

Cell Lysis: Piezoelectric Microchip for Cell Lysis through Cell–Microparticle Collision within a Microdroplet Driven by Surface Acoustic Wave Oscillation (Small 9/2019)

Shicai Wang, Xiaoqing Lv, Yue Su, Zhiyuan Fan, Weihao Fang, Jiazhi Duan, Shan Zhang, Baojin Ma, Feng Liu, Hongda Chen, Zhaoxin Geng, Hong Liu

Small· Volume 15· Issue 9

Abstract

In article number 1804593, Zhaoxin Geng, Hong Liu, and co-workers introduce a cell lysis method in a surface acoustic wave (SAW) microchip. When a biofluid droplet containing cells and microparticles is dropped on the working microchip, the cell membrane function is disrupted by the SAW. The intracellular contents are released after cell lysis, which can be used in disease diagnosis and stem cell therapy research.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Microfluidic and Bio-sensing Technologies

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Affiliations

State Key Laboratory of Crystal Materials Shandong University Jinan 250100 P. R. China

State Key Laboratory of Integrated Optoelectronics Institute of Semiconductors Chinese Academy of Sciences Beijing 100083 P. R. China

Center of Materials Science and Optoelectronics Engineering University of Chinese Academy of Sciences Beijing 100049 China

School of Information Engineering Minzu University of China Beijing 100081 P. R. China

Institute for Advanced Interdisciplinary Research Jinan University Jinan 250022 P. R. China

References

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