journal article·2018-03Open access

Cancer Therapy: Deep Tumor Penetrating Bioparticulates Inspired Burst Intracellular Drug Release for Precision Chemo‐Phototherapy (Small 12/2018)

Ruoning Wang, Yue Han, Bo Sun, Ziqiang Zhao, Yaw Opoku‐Damoah, Hao Cheng, Huaqing Zhang, Jianping Zhou, Yang Ding

Small· Volume 14· Issue 12

Abstract

In article number 1703110, Jianping Zhou, Yang Ding, and co-workers introduce a bioinspired particulate formulated with whole components of native HDLs and decorated with tumor-penetrating peptide iRGD. This proposal of penetrated HDLs (pHDLs) shares artificially endowed functions, leading to higher tumor accumulation and enhanced cellular uptake, burst intracellular drug release, and precision chemo-phototherapy without causing appreciable adverse effects.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Nanoplatforms for cancer theranostics

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Affiliations

State Key Laboratory of Natural Medicines Department of Pharmaceutics China Pharmaceutical University 24 Tongjiaxiang Nanjing 210009 China

The Center for Nanomedicine Johns Hopkins University School of Medicine Baltimore MD 21231 USA

Department of Ophthalmology Johns Hopkins University School of Medicine Baltimore MD 21231 USA

References

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