journal article·2014-04Open access

Plasmonic Nanostars: In Vivo Volumetric Photoacoustic Molecular Angiography and Therapeutic Monitoring with Targeted Plasmonic Nanostars (Small 8/2014)

Liming Nie, Shouju Wang, Xiaoyong Wang, Pengfei Rong, Ying Ma, Gang Liu, Peng Huang, Guangming Lu, Xiaoyuan Chen

Small· Volume 10· Issue 8

Abstract

Induced angiogenesis is a major hallmark of malignant tumor. As reported on page 1585, G. Lu, X. Chen, and co-workers design cyclic Arg-Gly-Asp (RGD) peptide conjugated plasmonic gold nanostars (RGD-GNS) to specifically target integrin avß3 overxpressed on tumor neovasculature. Quantitative volumetric angiography of tumors can be achieved with high resolution and deep penetration by a hemispherical photoacoustic imaging system. It also permits photothermal therapy and sequential therapeutic monitoring.
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Research context

OpenAlex topics: Nanoplatforms for cancer theranostics · Photoacoustic and Ultrasonic Imaging · Extracellular vesicles in disease

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Laboratory of Molecular Imaging and Nanomedicine (LOMIN) National Institute of Biomedical Imaging and Bioengineering (NIBIB) National Institutes of Health (NIH) Bethesda MD 20892 USA

Center for Molecular Imaging and Translational Medicine School of Public Health Xiamen University Xiamen 361005 China

Department of Medical Imaging, Jinling Hospital Clinical School of Medical College Nanjing University Nanjing 210002 China

References

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