journal article·2011-07-18Open access

Using Charge to Control the Functional Properties of Self‐Assembled Nanopores in Membranes

Michael X. Macrae, Diana Schlamadinger, Judy E. Kim, Michael Mayer, Jerry Yang

Small· Volume 7· Issue 14

Abstract

Light sensitive, semisynthetic ion channels allow for the modulation of multi­ple channel properties. Covalent attachment of a photoswitchable spiropyran group to the entrance of a gramicidin A ion channel enables reversible control of both conductance and channel lifetime, which show opposite trends in behavior at high and low salt concentrations. Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.
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Research context

OpenAlex topics: Advanced biosensing and bioanalysis techniques · Molecular Sensors and Ion Detection · Photoreceptor and optogenetics research

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