journal article·2008-01-18Open access

Stretched Cavity‐Assisted Molding of Micrometer and Submicrometer Photopolymerized Hydrogel Particles

Philips Laulia, Mary B Chan‐Park, Yehai Yan, Shen Qi Wang, Chang Ming Li, Yee Cheong Lam

Small· Volume 4· Issue 1

Abstract

Stretched cavity-assisted molding of particles is a novel method that can produce monodisperse submicrometer hydrogel particles (see image) loaded with a model protein drug, fluorescein-isothiocyanate-conjugated bovine serum albumin. The method avoids agitation, solvents, and high-energy input by forming the particles inside preformed cavities. This method has the potential to be generalized to prepare multilayered or targeted particles containing fragile drugs for the pharmaceutical industry.
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Research context

OpenAlex topics: 3D Printing in Biomedical Research · Innovative Microfluidic and Catalytic Techniques Innovation · Nanofabrication and Lithography Techniques

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