journal article·2025-03Open access

Bright and Stable Cyan Fluorescent RNA Enables Multicolor RNA Imaging in Live Escherichia coli (Small 9/2025)

Li Jiang, Fangting Zuo, Yuanyuan Pan, Ruilong Li, Yajie Shi, Xinyi Huang, Dasheng Zhang, Yingping Zhuang, Yuzheng Zhao, Qiuning Lin, Yi Yang, Linyong Zhu, Xianjun Chen

Small· Volume 21· Issue 9

Abstract

RNA Imaging In article number 2405165, Linyong Zhu, Xianjun Chen, and co-workers designed a novel cyan fluorescent RNA (FR) called Myosotis with high cellular brightness and photostability. Myosotis is biorthogonal to Pepper and Clivia FRs, allowing multiplex fluorescence imaging of RNA in live bacteria.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: RNA and protein synthesis mechanisms · Bacteriophages and microbial interactions · Cancer Research and Treatments

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Affiliations

Optogenetics & Synthetic Biology Interdisciplinary Research Center State Key Laboratory of Bioreactor Engineering East China University of Science and Technology 130 Mei Long Road Shanghai 200237 China

School of Biomedical Engineering Shanghai Jiao Tong University 800 Dong Chuan Road Shanghai 200240 China

Shanghai Frontiers Science Center of Optogenetic Techniques for Cell Metabolism School of Pharmacy East China University of Science and Technology 130 Mei Long Road Shanghai 200237 China

School of Bioengineering East China University of Science and Technology Shanghai 200237 China

Research Unit of New Techniques for Live‐cell Metabolic Imaging Chinese Academy of Medical Sciences Beijing 100730 China

References

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