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journal article·2024-12Open access

Single‐Atom Catalysts with Isolated Cu1‐N4 Sites for Atopic Dermatitis Cascade Catalytic Therapy via Activating PPAR Signaling (Small 52/2024)

Le Kuai, Fang Huang, Lijie Mao, Yi Ru, Jingsi Jiang, Jiankun Song, Si Chen, Ke Li, Yongyong Li, Haiqing Dong, Xiangyu Lu, Bin Li, Jianlin Shi

Small· Volume 20· Issue 52
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Source abstract

Abstract

Single-Atom Catalysts More in article number 2407365, Haiqing Dong, Xiangyu Lu, Bin Li, and co-workers present a single-atom copper catalyst (Cu1-N4 ISAC) with three antioxidant enzyme activities that can catalyze the conversion of O2•− to H2O2 and then to H2O. Such cascade catalytic properties make Cu1-N4 ISACs ameliorate atopic dermatitis symptoms via activating PPAR signaling.
Source: openalex_inverted_index · Quality: baseline

Research context

Catalysis & surfaces

OpenAlex topics: Tryptophan and brain disorders · Cholinesterase and Neurodegenerative Diseases · Histone Deacetylase Inhibitors Research

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Affiliations

Department of Dermatology Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Institute of Dermatology Shanghai University of Traditional Chinese Medicine Shanghai 200437 China

Department of Nephrology Tongji Hospital School of Medicine Tongji University Shanghai 200065 China

Key Laboratory of Spine and Spinal Cord Injury Repair and Regeneration Ministry of Education Tongji Hospital School of Medicine Tongji University Shanghai 200065 China

Department of Cardiology Shanghai Tenth People's Hospital Shanghai Frontiers Science Center of Nanocatalytic Medicine School of Medicine Tongji University Shanghai 200331 China

Shanghai Skin Disease Hospital Institute of Dermatology School of Medicine Tongji University Shanghai 200443 China

School of Materials Science and Engineering Hainan University Haikou 570228 China

Shanghai Institute of Ceramics Chinese Academy of Sciences Shanghai 200050 China

References

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