journal article·2024-03Open access

Metal–Organic Framework as a New Type of Magnetothermally‐Triggered On‐Demand Release Carrier (Small 12/2024)

Xueying Ge, Jeotikanta Mohapatra, Enya Silva, Guihua He, Lingshan Gong, Tengteng Lyu, Richa P. Madhogaria, Xin Zhao, Yuchuan Cheng, Abdullah M. Al‐Enizi, Ayman Nafady, Jian Tian, J. Ping Liu, Manh‐Huong Phan, Francesca Taraballi, Roderic I. Pettigrew, Shengqian Ma

Small· Volume 20· Issue 12

Abstract

Drug Release Technology In article number 2306940, Jian Tian, Shengqian Ma, and co-workers developed a novel magnetothermally-triggered drug release carrier. Created using a controlled encapsulation method, this carrier fully fixes and confines iron oxide nanoparticles (IONPs) within metal-organic frameworks (MOFs), preserving the MOF's morphology and porosity and effectively segregating IONPs. It enhances heating efficiency and shows promise for magneto-thermally modulated drug dosing at tumor sites, offering potential advancements in cancer treatment.
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Research context

OpenAlex topics: Lanthanide and Transition Metal Complexes · Metal-Organic Frameworks: Synthesis and Applications

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Affiliations

Department of Chemistry University of North Texas Denton Texas 76201 USA

Engineering Medicine (EnMed) Texas A&M University and Houston Methodist Hospital Houston Texas 77030 USA

Department of Physics The University of Texas at Arlington Arlington Texas 76019 USA

Department of Physics University of South Florida Tampa Florida 33620 USA

Key Laboratory of Combinatorial Biosynthesis and Drug Discovery (MOE) Hubei Province Engineering and Technology Research Center for Fluorinated Pharmaceuticals School of Pharmaceutical Sciences Wuhan University Wuhan 430071 P. R. China

J. Mike Walker ‘66 Department of Mechanical Engineering Texas A&M University College Station TX 77843 USA

Zhejiang Key Laboratory of Additive Manufacturing Materials Ningbo Institute of Material Technology and Engineering Chinese Academy of Sciences Ningbo 315201 P. R. China

Department of Chemistry College of Science King Saud University Riyadh 11451 Saudi Arabia

Center for Musculoskeletal Regeneration Orthopedics and Sports Medicine Houston Methodist Hospital Houston Methodist Academic Institute Houston Texas 77030 USA

References

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