A Biomimetic Peptide Functions as Specific Extracellular Matrix for Quiescence of Stem Cells against Intervertebral Disc Degeneration (Small 44/2023)
Source abstract
Abstract
Intervertebral Disc Degeneration A biomimetic peptide (OAFF) binds to C-X-C motif chemokine receptor 1 (CXCR1) and forms fibrous networks on nucleus pulposus stem cells (NPSCs) for mimicking extracellular matrix formation, which induces NPSCs quiescence and ultimately overcomes obstacle in intradiscal injection therapy. More details can be found in article number 2300578 by Lei Wang, Bo Huang, and co-workers.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Spine and Intervertebral Disc Pathology · Medical Imaging and Analysis
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Department of Orthopedics Xinqiao Hospital Army Medical University Chongqing 400037 P. R. China
CAS Center for Excellence in Nanoscience CAS Key Laboratory for Biological Effects of Nanomaterials and Nanosafety National Center for Nanoscience and Technology (NCNST) Beijing 100190 P. R. China
Clinical Medicine Research Center Xinqiao Hospital Army Medical University Chongqing 400037 P. R. China
Department of Orthopedics Shanghai General Hospital Shanghai Jiaotong University Shanghai 200080 P. R. China
References
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