DataVXSmallPaper
journal article·2022-11

Vitality‐Enhanced Dual‐Modal Tracking System Reveals the Dynamic Fate of Mesenchymal Stem Cells for Stroke Therapy (Small 47/2022)

Jianpei Xu, Yuwen Zhang, Yipu Liu, Yang You, Fengan Li, Yu Chen, Laozhi Xie, Shiqiang Tong, Songlei Zhou, Kaifan Liang, Yukun Huang, Gan Jiang, Qingxiang Song, Ni Mei, Fenfen Ma, Xiaoling Gao, He Wang, Jun Chen

Small· Volume 18· Issue 47
Publisher page
Source abstract

Abstract

Stroke Therapy In article number 2203431, Xiaoling Gao, He Wang, Jun Chen, and co-workers engineer mesenchymal stem cells (MSCs) with near-infrared (NIR) and magnetic resonance (MR) dual-modal tracking nanoparticles via a bioorthogonal method. An antioxidant layer covered on the MSCs' surface enhances their vitality in a harsh stroke microenvironment. The vitality-enhanced MSCs remigrate from penumbra to the infarct core act just like firemen struggling with a fire to save lives.
Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Neurological Disorders and Treatments · Advanced Nanomaterials in Catalysis · Neurological Disease Mechanisms and Treatments

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Pharmaceutics School of Pharmacy & Shanghai Pudong Hospital Key Laboratory of Smart Drug Delivery Ministry of Education Fudan University 826 Zhangheng Road Shanghai 201203 P. R. China

Institute of Science and Technology for Brain‐Inspired Intelligence & Department of Neurology Zhongshan Hospital Fudan University 825 Zhangheng Road Shanghai 201203 P. R. China

Department of Pharmacology and Chemical Biology State Key Laboratory of Oncogenes and Related Genes Shanghai Universities Collaborative Innovation Center for Translational Medicine Shanghai Jiao Tong University School of Medicine 280 South Chongqing Road Shanghai 200025 P. R. China

Shanghai Center for Drug Evaluation and Inspection 781 Cailun Road Shanghai 201203 P. R. China

References

Reference metadata was not supplied for this record.