Cancer Nanotherapy: Investigating Subcellular Compartment Targeting Effect of Porous Coordination Cages for Enhancing Cancer Nanotherapy (Small 47/2018)
Source abstract
Abstract
In article number 1802709, Jean-Philippe Pellois, Hong-Cai Zhou, and co-workers uncover a series of metal-organic cages as novel and superior cargo delivery scaffolds that target subcellular compartments, such as the nucleus, cytoplasm, and membrane, within a living cell. Through manipulation of the overall charge and surface affinity of the cages, the “nano-bio” interactions between several cellular barriers and the nano cages can be tuned. This finding provides a unique delivery platform for cell imaging, cancer therapy, and gene editing.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Nanoplatforms for cancer theranostics · Advanced Nanomaterials in Catalysis · Metal-Organic Frameworks: Synthesis and Applications
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Affiliations
Department of Chemistry Texas A&M University College Station TX 77843 USA
Beijing National Laboratory for Molecular Sciences CAS Key Laboratory of Analytical Chemistry for Living Biosystems Institute of Chemistry Chinese Academy of Sciences Beijing 100190 China
Department of Biology Texas A&M University College Station TX 77843 USA
Department of Biochemistry and Biophysics Texas A&M University College Station TX 77843 USA
References
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