journal article·2018-02Open access

Osteoarthritis Therapy: Nanocrystal–Polymer Particles: Extended Delivery Carriers for Osteoarthritis Treatment (Small 8/2018)

Pierre Maudens, Christian Alexander Seemayer, Cédric Thauvin, Cem Gabay, Olivier Jordan, Eric Allémann

Small· Volume 14· Issue 8

Abstract

In article number 1703108, Eric Allémann and co-workers formulate a drug delivery system based on nanocrystal-polymer particles. Nanocrystals of drug are embedded in biodegradable microparticles to provide a long-term, intra-articular osteoarthritis therapy. This treatment is efficient in reducing the frequency of injections, and may fulfill an unmet medical need; the reconstitution of the cartilage. This approach shows promise as a safe drug delivery system to locally treat diseases over extended periods of time with a high drug loading.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Neurological Disorders and Treatments

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Affiliations

School of Pharmaceutical Sciences University of Geneva University of Lausanne CH‐1211 Geneva 4 Switzerland

Department of Clinical Science Idorsia Pharmaceuticals Ltd. CH‐4123 Allschwil Switzerland

Division of Rheumatology Department of Internal Medicine Specialties University Hospital and Department of Pathology and Immunology School of Medicine University of Geneva CH‐1211 Geneva 4 Switzerland

References

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