journal article·2021-08Open access

SERS Quantification of Galunisertib Delivery in Colorectal Cancer Cells by Plasmonic‐Assisted Diatomite Nanoparticles (Small 34/2021)

Stefano Managò, Chiara Tramontano, Donatella Delle Cave, Giovanna Chianese, Gianluigi Zito, Luca De Stefano, Monica Terracciano, Enza Lonardo, Anna Chiara De Luca, Ilaria Rea

Small· Volume 17· Issue 34

Abstract

Drug Delivery Systems In article number 2101711, Enza Lonardo, Anna Chiara De Luca, Ilaria Rea, and co-workers demonstrate the small molecule Galunisertib with anticancer activity loaded inside a hybrid multifunctional nanosystem made of porous biosilica covered by plasmonic gold nanoparticles. The pH-triggered-LY release inducing mesenchymal to epithelial transition in colorectal cancer cells is monitored and quantified with sub-femtogram resolution by intracellular SERS analysis.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Nanoparticle-Based Drug Delivery · Advanced Nanomaterials in Catalysis · Nanoplatforms for cancer theranostics

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

National Research Council Institute of Biochemistry and Cell Biology Naples 80131 Italy

National Research Council Institute of Applied Sciences and Intelligent Systems Unit of Naples Naples 80131 Italy

University of Naples Federico II Department of Pharmacy Naples 80131 Italy

National Research Council Institute of Genetics and Biophysics Naples 80131 Italy

References

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