journal article·2016-10Open access

Cellular Uptake: Size‐Dependent Cellular Uptake of DNA Functionalized Gold Nanoparticles (Small 40/2016)

Alexis C. Wong, David W. Wright

Small· Volume 12· Issue 40

Abstract

On page 5592, A. C. Wong and D. W. Wright demonstrate that cells internalize small DNA functionalized gold nanoparticles (DNA-AuNPs) in higher amounts than large DNA-AuNPs. DNA conformation, DNA density, and surface charge do not reliably predict nanoparticle accumulation in cells. These results inform the design of intracellular DNA-AuNP probes that have enhanced cellular transfection.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: RNA Interference and Gene Delivery

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Affiliations

Department of Chemistry Vanderbilt University Station B 351822 Nashville TN 37235‐1822 USA

References

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