Nanotube Arrays: Bioinspired Patterning with Extreme Wettability Contrast on TiO₂ Nanotube Array Surface: A Versatile Platform for Biomedical Applications (Small 17/2013)

The construction of erasable and rewritable superhydrophilic–superhydrophobic patterns on novel TiO2 nanotube arrays is described by Y. K. Lai, C. J. Lin, L. F. Chi, and co-workers on page 2945. The patterned superhydrophobic surface is an excellent 2D scaffold for site-selective cell adhesion and reversible protein absorption, and acts as a template to deposit or grow well-defined 3D spatially functional biomaterials (e.g., CaP, Ag, biological molecules, and drugs). Furthermore, the functional composite patterning allows specificity for SERS sensors, antibacterial agents, targeted drug delivery and cell bioassays.