journal article·2020-06Open access

Therapeutic Bacteria: Surface Modifications for Improved Delivery and Function of Therapeutic Bacteria (Small 25/2020)

Ava M. Vargason, Shruti Santhosh, Aaron C. Anselmo

Small· Volume 16· Issue 25

Abstract

In article number 2001705, Aaron C. Anselmo and co-workers present a platform to modify probiotics with antibodies that specifically attach to the intestinal lumen following oral delivery. The antibody modification enables adherence to the mucosa, leading to the establishment of an intestinal niche that reduces colonization time and improves overall exposure to the therapeutic compared to unmodified probiotics.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Probiotics and Fermented Foods · Gut microbiota and health

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Division of Pharmacoengineering and Molecular Pharmaceutics University of North Carolina at Chapel Hill Eshelman School of Pharmacy Chapel Hill NC 27599 USA

References

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