journal article·2021-04

Silicasome Nanocarriers: Development of Facile and Versatile Platinum Drug Delivering Silicasome Nanocarriers for Efficient Pancreatic Cancer Chemo‐Immunotherapy (Small 14/2021)

Xiangsheng Liu, Jinhong Jiang, Chong Hyun Chang, Yu‐Pei Liao, Jared J. Lodico, Ivanna Tang, Emily Zheng, Waveley Qiu, Matthew Lin, Xiang Wang, Ying Ji, Kuo‐Ching Mei, Andre E. Nel, Huan Meng

Small· Volume 17· Issue 14
Publisher page

Abstract

Effective delivery of activated oxaliplatin to pancreatic cancer achieved by a tailored silicasome nanocarrier is reported by Andre E. Nel, Huan Meng, and co-workers in article number 2005993. This provides a strong immunogenic cell death stimulus that turns the “cold” immunological status into “hot” at tumor site, enabling superior chemo-immunotherapy synergy with anti-PD-1.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Nanoplatforms for cancer theranostics · Cancer Research and Treatments · Nanoparticle-Based Drug Delivery

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Division of Nanomedicine Department of Medicine University of California Los Angeles CA 90095 USA

California NanoSystems Institute University of California Los Angeles CA 90095 USA

Department of Physics and Astronomy University of California Los Angeles CA 90095 USA

References

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