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journal article·2020-05Open access

Polymeric Nanoparticles: Polymeric Nanoparticles with Neglectable Protein Corona (Small 18/2020)

Irina Alberg, Stefan Kramer, Meike Schinnerer, Qizhi Hu, Christine Seidl, Christian Leps, Natascha Drude, Diana Möckel, Cristianne Rijcken, Twan Lammers, Mustafa Diken, Michael Maskos, Svenja Morsbach, Katharina Landfester, Stefan Tenzer, Matthias Barz, Rudolf Zentel

Small· Volume 16· Issue 18
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Source abstract

Abstract

Currently it is assumed that each nanoparticle rapidly adsorbs proteins when it enters the living organism. However, this is not a general property of all nanosized drug delivery systems. In article number 1907574, Stefan Tenzer, Matthias Barz, Rudolf Zentel, and co-workers present three self-assembled polymeric structures, which are effectively free of a protein corona and additionally show prolonged circulation profiles in vivo.
Source: openalex_inverted_index · Quality: baseline

Research context

PolymersNanomaterials

OpenAlex topics: Nanoparticle-Based Drug Delivery

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Affiliations

Institute of Organic Chemistry Johannes Gutenberg University Mainz Duesbergweg 10‐14 Mainz D‐55128 Germany

Institute of Physical Chemistry Johannes Gutenberg University Mainz Duesbergweg 10‐14 Mainz D‐55128 Germany

Cristal Therapeutics Oxfordlaan 55 Maastricht 6229 EV The Netherlands

Institute for Immunology University Medical Center of Mainz Langenbeckstr. 1 Mainz 55131 Germany

Department of Nanomedicine and Theranostics Institute for Experimental Molecular Imaging RWTH Aachen University Clinic Forckenbecktrasse 55 Aachen 52074 Germany

TRON ‐ Translational Oncology at the University Medical Center of Johannes Gutenberg University gGmbH Freiligrathstr. 12 Mainz 55131 Germany

Fraunhofer Institute for Microengineering and Microsystems IMM Carl‐Zeiss‐Str. 18‐20 Mainz 55129 Germany

Max Planck Institute for Polymer Research Ackermannweg 10 Mainz 55128 Germany

References

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