journal article·2018-06Open access

Single Cell Analysis: Label‐Free Optofluidic Nanobiosensor Enables Real‐Time Analysis of Single‐Cell Cytokine Secretion (Small 26/2018)

Xiaokang Li, Maria Soler, Crispin Szydzik, Khashayar Khoshmanesh, Julien Schmidt, George Coukos, Arnan Mitchell, Hatice Altug

Small· Volume 14· Issue 26

Abstract

Dynamic monitoring and analysis of protein secretion from single cells remain challenges. In article number 1800698, Hatice Altug and co-workers present an optofluidic nanoplasmonic biosensor for real-time monitoring of cytokine secretion. The label-free system enables the detection and quantification of protein secretions from single cells while maintaining controlled conditions for cell activity. With integration into multifunctional microfluidic systems, this biosensor can be a powerful tool to characterize single-cell signaling for basic and clinical research.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Advanced Biosensing Techniques and Applications · Biosensors and Analytical Detection

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Affiliations

Institute of Bioengineering École Polytechnique Fédérale de Lausanne (EPFL) CH‐1015 Lausanne Switzerland

School of Engineering RMIT University Melbourne 3001 Australia

Ludwig Institute for Cancer Research University of Lausanne and Department of Oncology University of Lausanne CH‐1007 Lausanne Switzerland

References

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