journal article·2016-04Open access

Nanomedicine: The Protein Corona of Plant Virus Nanoparticles Influences their Dispersion Properties, Cellular Interactions, and In Vivo Fates (Small 13/2016)

Andrzej S. Pitek, Amy M. Wen, Sourabh Shukla, Nicole F. Steinmetz

Small· Volume 12· Issue 13

Abstract

The interactions between targeted plant virus-based nanoparticles and the proteins they encounter when injected into the bloodstream are investigated by N.F. Steinmetz and co-workers, on page 1758. The identification of which plasma proteins bind to the surface of plant viral nanoparticles and how that affects their dispersion, targeting, and clearance by the mononuclear phagocytic system, is demonstrated. The consequences of these interactions on biodistribution are also shown.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Transgenic Plants and Applications · Plant Virus Research Studies · Bacteriophages and microbial interactions

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Biomedical Engineering Case Western Reserve University Cleveland OH 44106 USA

Department of Radiology Case Western Reserve University Cleveland OH 44106 USA

Department of Materials Science and Engineering Case Western Reserve University Cleveland OH 44106 USA

Department of Macromolecular Science and Engineering Case Western Reserve University Cleveland OH 44106 USA

Case Comprehensive Cancer Center Case Western Reserve University Cleveland OH 44106 USA

References

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