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journal article·2025-04Open access

EGCG‐enabled Deep Tumor Penetration of Phosphatase and Acidity Dual‐responsive Nanotherapeutics for Combinatory Therapy of Breast Cancer (Small 14/2025)

Mengxue Zhou, Chuang Zhou, Huan Geng, Zhiwei Huang, Zhiyuan Lin, Ying Wang, Yin Zhu, Jiang Shi, Junfeng Tan, Li Guo, Yanni Zhao, Yue Zhang, Qunhua Peng, Haijun Yu, Weidong Dai, Haipeng Lv, Zhi Lin

Small· Volume 21· Issue 14
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Source abstract

Abstract

Breast Cancer In article number 2406245, Weidong Dai, Haipeng Lv, Zhi Lin, and co-workers reveal the mechanism through which EGCG alleviates tumor fibrosis to enable deep penetration of dual-responsive nanotherapeutics. EGCG and the dual-responsive nanodrug achieved synergistic starvation-/chemodynamic-/chemo-therapy to eliminate TNBC cells and prevent lung metastasis.
Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Nanoplatforms for cancer theranostics · Graphene and Nanomaterials Applications · Nanoparticle-Based Drug Delivery

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Key Laboratory of Tea Biology and Resource Utilization of Ministry of Agriculture Tea Research Institute Chinese Academy of Agricultural Sciences Hangzhou 310008 P. R. China

School of Food and Biological Engineering Shaanxi University of Science & Technology Xi'an 710021 P. R. China

Department of Orthopedic Surgery The Second Affiliated Hospital Zhejiang University School of Medicine Hangzhou Zhejiang 310009 P. R. China

MOE Frontiers Science Center for Rare Isotopes Lanzhou University Lanzhou 730000 P. R. China

Center of Pharmaceutics Shanghai Institute of Materia Medica Chinese Academy of Sciences Shanghai 201203 P. R. China

References

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