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journal article·2022-06Open access

A Versatile Electrochemical Biosensor for the Detection of Circulating MicroRNA toward Non‐Small Cell Lung Cancer Diagnosis (Small 22/2022)

Fanyu Meng, Wenjun Yu, Changqiang Chen, Susu Guo, Xiaoting Tian, Yayou Miao, Lifang Ma, Xiao Zhang, Yongchun Yu, Lin Huang, Kun Qian, Jiayi Wang

Small· Volume 18· Issue 22
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Source abstract

Abstract

Cancer Diagnostics In article number 2200784, Kun Qian, Jiayi Wang, and co-workers develop a versatile electrochemical biosensing system for circulating miRNA detection by DNAzyme cleavage cycling amplification and hybridization chain reaction amplification. By profiling miRNA in a non-small-cell lung cancer cohort, this designed liquid biopsy strategy shows high efficiency and sensitivity for early diagnosis and prognosis toward clinical use.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: MicroRNA in disease regulation · RNA modifications and cancer

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Country Department of Clinical Laboratory Medicine Shanghai Chest Hospital Shanghai Jiao Tong University Shanghai 200030 China

Shanghai Institute of Thoracic Oncology Shanghai Chest Hospital Shanghai Jiao Tong University Shanghai 200030 China

Department of Laboratory Medicine Ruijin Hospital Shanghai Jiao Tong University School of Medicine Shanghai 201801 China

State Key Laboratory for Oncogenes and Related Genes School of Biomedical Engineering Institute of Medical Robotics and Med‐X Research Institute Shanghai Jiao Tong University Shanghai 200030 China

References

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