journal article·2021-08Open access

Controlled CRISPR‐Cas9 Ribonucleoprotein Delivery for Sensitized Photothermal Therapy (Small 33/2021)

Chao Chen, Yupei Ma, Shiyu Du, Yueyao Wu, Peiliang Shen, Tao Yan, Xueqing Li, Yujun Song, Zhengbao Zha, Xin Han

Small· Volume 17· Issue 33

Abstract

Synergistic Therapy In article number 2101155, Yujun Song, Zhengbao Zha, Xin Han, and co-workers report a novel thermo-responsive nanotherapeutic platform, which is triggered by 808 nm near-infrared light irradiation. This exogenously controlled method can be used in combination tumor therapy, including gene-therapy, mild-photothermal therapy, and chemotherapy, which provides a versatile strategy for controlled gene editing and drug release for synergistic therapy with maximizing efficacy and minimizing side-effects.
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Research context

OpenAlex topics: Nanoplatforms for cancer theranostics · CRISPR and Genetic Engineering

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Affiliations

Department of Biochemistry and Molecular Biology School of Medicine & Holistic Integrative Medicine Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization Nanjing University of Chinese Medicine Nanjing 210023 China

School of Food and Biological Engineering Hefei University of Technology Hefei 230009 China

College of Engineering and Applied Sciences State Key Laboratory of Analytical Chemistry for Life Science Nanjing University Nanjing 210023 China

References

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