DataVXSmallPaper
journal article·2015-09Open access

Drug Delivery: Tumor‐Triggered Controlled Drug Release from Electrospun Fibers Using Inorganic Caps for Inhibiting Cancer Relapse (Small 34/2015)

Xin Zhao, Ziming Yuan, Lara Yildirimer, Jingwen Zhao, Zhi Yuan (William) Lin, Zhi Cao, Guoqing Pan, Wenguo Cui

Small· Volume 11· Issue 34
Publisher pageOpen full text
Source abstract

Abstract

A smart, tumor-trigged, controlled drug release using inorganic “caps” with CO32− functional groups in electrospun fibers is reported by W. Cui and co-workers on page 4284 to inhibit cancer relapse. When the drug-loaded intelligent electrospun fibers encounter pathological acidic environments, the inorganic gates will react with the acids and produce CO2 gas, which enables water penetration into the core of the fibers to induce rapid drug release.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Electrospun Nanofibers in Biomedical Applications · Nanoparticle-Based Drug Delivery · Supramolecular Self-Assembly in Materials

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Department of Orthopedics The First Affiliated Hospital of Soochow University Orthopedic Institute Soochow University 708 Renmin Road Suzhou Jiangsu 215006 P. R. China

Department of General Surgery Shanghai Sixth People's Hospital Shanghai Jiao Tong University School of Medicine 600 Yishan Road Shanghai 200233 P. R. China

Centre for Nanotechnology and Regenerative Medicine UCL Division of Surgery and Interventional Science University College London London WC1E 6AU UK

Department of Chemistry University of California Berkeley CA 94720 USA

References

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