Hypoxia‐Responsive Photosensitizer Targeting Dual Organelles for Photodynamic Therapy of Tumors (Small 1/2023)
Source abstract
Abstract
Photodynamic Therapy of Tumors In article number 2205440, Zhiyang Liu, Quan Li, and co-workers exploit the hypoxic properties of solid tumors to construct a hypoxia-responsive photosensitizer. When the non-fluorescent hypoxia-responsive photosensitizer enters the hypoxic tumors, it is reduced by the overexpressed azoreductase to generate the fluorescent photosensitizer with the aggregation-induced emission property, which can realize the fluorescence-activatable image-guided photodynamic therapy with dual-organelle (lipid droplets and lysosomes) targeting.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Nanoplatforms for cancer theranostics · Cancer, Hypoxia, and Metabolism · Advanced Nanomaterials in Catalysis
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Institute of Advanced Materials and School of Chemistry and Chemical Engineering Southeast University Nanjing 211189 P. R. China
Advanced Materials and Liquid Crystal Institute and Chemical Physics Interdisciplinary Program Kent State University Kent OH 44242 USA
References
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