DataVXSmallPaper
journal article·2022-05

Microfluidic Impedance‐Deformability Cytometry for Label‐Free Single Neutrophil Mechanophenotyping (Small 18/2022)

Chayakorn Petchakup, Haoning Yang, Lingyan Gong, Linwei He, Hui Min Tay, Rinkoo Dalan, Aram J. Chung, King Ho Holden Li, Han Wei Hou

Small· Volume 18· Issue 18
Publisher page
Source abstract

Abstract

Neutrophil Mechanophenotyping The intrinsic biophysical states of neutrophils are often associated with immune dysfunctions. In article number 2104822, Han Wei Hou and co-workers report an “optics-free” microfluidic biophysical cytometer for impedance-based single cell electro-mechano-phenotyping. The developed platform integrates elasto-inertial focusing, hydrodynamic cell pinching, and multifrequency differential impedance sensing to enable label-free and multi-parametric neutrophil profiling towards rapid clinical diagnostics.
Source: openalex_inverted_index · Quality: baseline

Research context

OpenAlex topics: Microfluidic and Bio-sensing Technologies · Biosensors and Analytical Detection · Cell Image Analysis Techniques

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

School of Mechanical and Aerospace Engineering Nanyang Technological University 50 Nanyang Avenue Singapore 639798 Singapore

Endocrinology Department Tan Tock Seng Hospital 11 Jln Tan Tock Seng Road Singapore 308433 Singapore

School of Biomedical Engineering Korea University Seoul 02841 Republic of Korea

Interdisciplinary Program in Precision Public Health Korea University Seoul 02841 Republic of Korea

Lee Kong Chian School of Medicine Nanyang Technological University 11 Mandalay Road, Clinical Sciences Building Level 11 Singapore 308232 Singapore

References

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