DataVXSmallPaper
journal article·2018-06Open access

Graphene Biotransformation: Biotransformation and Biological Interaction of Graphene and Graphene Oxide during Simulated Oral Ingestion (Small 24/2018)

Daniela Guarnieri, Paola Sánchez‐Moreno, Antonio Esaú Del Rio Castillo, Francesco Bonaccorso, Francesca Gatto, Giuseppe Bardi, Cristina Martín, Ester Vázquez, Tiziano Catelani, Stefania Sabella, Pier Paolo Pompa

Small· Volume 14· Issue 24
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Source abstract

Abstract

In article number 1800227, Stefania Sabella, Pier Paolo Pompa and co-workers analyze the biotransformation and biological interaction of graphene and graphene oxide through an oral ingestion assay simulating chronic exposure. No structural changes/degradation of the nanomaterials are detected during their passage through the gastrointestinal tract, suggesting their biopersistence when administered by oral route. Digested graphene did not affect intestinal barrier integrity, though long-term adverse effects cannot be excluded.
Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Graphene and Nanomaterials Applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Nanobiointeractions & Nanodiagnostics Istituto Italiano di Tecnologia (IIT) Via Morego, 30 16163 Genova Italy

Graphene Labs Istituto Italiano di Tecnologia Via Morego, 30 16136 Genova Italy

Department of Engineering for Innovation University of Salento 73100 Lecce Italy

Departamento de Química Orgánica Facultad de Ciencias y Tecnologías Químicas Universidad de Castilla‐La Mancha 13071 Ciudad Real Spain

Instituto Regional de Investigación Científica Aplicada (IRICA) Universidad de Castilla‐La Mancha 13071 Ciudad Real Spain

Electron Microscopy Facility Istituto Italiano di Tecnologia Via Morego 30 16163 Genova Italy

Drug Discovery and Development Department Istituto Italiano di Tecnologia Via Morego, 30 16136 Genova Italy

References

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