Biosensing: A General Strategy of Aerolysin Nanopore Detection for Oligonucleotides with the Secondary Structure (Small 18/2018)
Source abstract
Abstract
Aerolysin-based direct analysis of oligonucleotides with secondary structure (e.g., G-quadruplex) remains a challenge. In article number 1704520, Yi-Lun Ying, Yi-Tao Long, and co-workers present a strategy employing an aerolysin nanopore to analyze structured oligonucleotides that are extended to 30 bases in length by a cation-regulation mechanism. This method can in principle be applied to genetic and epigenetic biosensing, making it practical for diagnostics.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Nanopore and Nanochannel Transport Studies · Advanced biosensing and bioanalysis techniques · Fuel Cells and Related Materials
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Affiliations
Key Laboratory for Advanced Materials, School of Chemistry and Molecular Engineering East China University of Science and Technology Shanghai 200237 P. R. China
References
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