DataVXSmallPaper
journal article·2019-06Open access

Cell Delivery: Highly Porous Microcarriers for Minimally Invasive In Situ Skeletal Muscle Cell Delivery (Small 25/2019)

Ranjith Kumar Kankala, Jia Zhao, Chen‐Guang Liu, Xiao‐Jie Song, Da‐Yun Yang, Kai Zhu, Shi‐Bin Wang, Yu Shrike Zhang, Ai‐Zheng Chen

Small· Volume 15· Issue 25
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Source abstract

Abstract

In article number 1901397, Yu Shrike Zhang, Ai-Zheng Chen, and co-workers fabricate highly open porous microspheres (HOPMs) using a microfluidic technique for harboring skeletal myoblasts towards cell delivery applications in situ. The structure of the HOPMs conveniently provides a favorable microenvironment for cell adhesion and proliferation, improved cell retention and vascularization, as well as partial myoblast differentiation. These modular cell-laden microcarriers potentially allow for in situ tissue construction after minimally invasive delivery, providing a convenient means for regeneration medicine. The caption was modified on 25 June, 2019 after initial online publication.
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Research context

OpenAlex topics: Mesenchymal stem cell research · Bone Tissue Engineering Materials · Electrospun Nanofibers in Biomedical Applications

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Institute of Biomaterials and Tissue Engineering Huaqiao University Xiamen 361021 P. R. China

Fujian Provincial Key Laboratory of Biochemical Technology Huaqiao University Xiamen 361021 P. R. China

Fujian Key Laboratory for Translational Research in Cancer and Neurodegenerative Diseases Institute for Translational Medicine School of Basic Medical Sciences Fujian Medical University Fuzhou Fujian 350108 P. R. China

Department of Cardiac Surgery Zhongshan Hospital Fudan University Shanghai 200032 P. R. China

Division of Engineering in Medicine Brigham and Women's Hospital Department of Medicine Harvard Medical School Cambridge MA 02139 USA

References

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