Zwitterionic Coatings: Zwitterionic‐Coated “Stealth” Nanoparticles for Biomedical Applications: Recent Advances in Countering Biomolecular Corona Formation and Uptake by the Mononuclear Phagocyte System (Small 13/2014)
Source abstract
Abstract
The development of nanoparticle assemblies for in vivo applications is hampered by the fact that most nanoparticles are scavenged by the mononuclear phagocyte system, in a process commencing with the rapid adsorption of serum proteins, including antibodies, to their surface. On page 2516, L. Spiccia, H. Stephan, B. Graham, and colleagues summarize the recent efforts to develop zwitterionic-coatings, which resist the formation of such a “biomolecular corona”, providing promising platforms for future nanomedicine design.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Nanoparticle-Based Drug Delivery · Supramolecular Self-Assembly in Materials · RNA Interference and Gene Delivery
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
Affiliations
Institute of Radiopharmaceutical Cancer Research Helmholtz‐Zentrum Dresden‐Rossendorf PF 510119 Dresden 01314 Germany
Monash Institute of Pharmaceutical Sciences Monash University Parkville VIC 3052 Australia
School of Chemistry Monash University Clayton VIC 3800 Australia
References
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