journal article·2020-10

Cancer Therapy: Transformable Dual‐Inhibition System Effectively Suppresses Renal Cancer Metastasis through Blocking Endothelial Cells and Cancer Stem Cells (Small 40/2020)

Lu Wang, Yulin Lv, Cong Li, Guang Yang, Bo Fu, Qiang Peng, Lingrui Jian, Dayong Hou, Jiaqi Wang, Changhao Zhao, Peipei Yang, Kuo Zhang, Lei Wang, Ziqi Wang, Hao Wang, Wanhai Xu

Small· Volume 16· Issue 40
Publisher page

Abstract

In article number 2004548, Lei Wang, Ziqi Wang, Hao Wang, Wanhai Xu, and co-workers propose a transformable dual-inhibition system (TDS) based on a self-assembly peptide to reduce metastasis of renal cancer via the inhibition of neovascular endothelial cells and cancer stem cells simultaneously. The TDS has great value in suppressing renal cancer metastasis. Additionally, this newly developed TDS also gives new ideas for in situ constructed modular functional materials and diverse bio-applications.
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Research context

OpenAlex topics: Nanoplatforms for cancer theranostics · Chemical Synthesis and Analysis

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Affiliations

Department of Urology (Heilongjiang Key Laboratory of Scientific Research in Urology) The Fourth Hospital of Harbin Medical University Harbin 150001 China

NHC Key Laboratory of Molecular Probes and Targeted Diagnosis and Therapy Harbin Medical University Harbin 150001 China

Department of Neurosurgery The First Affiliated Hospital of Harbin Medical University Harbin 150001 China

CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety CAS Center for Excellence in Nanoscience National Center for Nanoscience and Technology (NCNST) Beijing 100190 China

References

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