Picoanalysis: Picoanalysis of Drugs in Biofluids with Quantitative Label‐Free Surface‐Enhanced Raman Spectroscopy (Small 47/2018)
Source abstract
Abstract
In article number 1802392, Lev T. Perelman and co-workers report a quantitative label-free surface-enhanced Raman spectroscopy (SERS) method for identifying and quantifying drugs at ultralow concentrations. Self-assembled gold nanoclusters entrap drug molecules and laser light excites the surface plasmon resonance, yielding a large SERS signal from the molecule trapped near the hot spot, allowing measurements of drugs in urine samples at clinically relevant concentrations.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Spectroscopy Techniques in Biomedical and Chemical Research · Gold and Silver Nanoparticles Synthesis and Applications
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Affiliations
Center for Advanced Biomedical Imaging and Photonics Beth Israel Deaconess Medical Center Harvard University Boston MA 02215 USA
Department of Pathology Beth Israel Deaconess Medical Center Harvard University Boston MA 02215 USA
References
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