Cancer Diagnosis: A Universal Upconversion Sensing Platform for the Sensitive Detection of Tumour‐Related ncRNA through an Exo III‐Assisted Cycling Amplification Strategy (Small 10/2018)
Source abstract
Abstract
In article number 1703858, Xingcai Wu, Jun-Jie Zhu, and co-workers report a universal and sensitive upconversion sensing nanoplatform for detecting tumor-related non-coding RNA. The sensitivity of the probe is improved by tuning the number of DNA units on the gold nanoparticles, and an exonuclease III-assisted target cycling amplification strategy improves the sensitivity and achieves the universality of this sensing nanoplatform. Through this method, the expression level of microRNA-21 in human breast cancer cell lysate is successfully measured, suggesting its potential in cancer diagnosis.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Advanced biosensing and bioanalysis techniques
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Affiliations
State Key Laboratory of Analytical Chemistry for Life Science Key Laboratory of Mesoscopic Chemistry of MOE School of Chemistry and Chemical Engineering Nanjing University Nanjing 210023 China
Anhui Key Laboratory of Spin Electron and Nanomaterials (Cultivating Base) School of Chemistry and Chemical Engineering Suzhou University Suzhou Anhui 234000 China
Key Laboratory for Organic Electronics and Information Displays Institute of Advanced Materials (IAM) Nanjing University of Posts and Telecommunications Nanjing 210023 China
References
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