article·2017-07-01Open access

Microfluidics: Inertial Microfluidic Cell Stretcher (iMCS): Fully Automated, High-Throughput, and Near Real-Time Cell Mechanotyping (Small 28/2017)

Yanxiang Deng, Steven Davis, Fan Yang, Kevin S. Paulsen, Maneesh Kumar, Rebecca Sinnott, Xianhui Wang, Douglas S. Conklin, Assad A. Oberai, Jason I. Herschkowitz, Aram J. Chung

Abstract

In article number 1700705, Aram J. Chung and co-workers report a novel inertial microfluidic cell stretcher capable of characterizing large populations of single-cell deformability near real-time in a fully automated manner. This study opens up a new path to practically measure large populations of single-cell quantitative mechanical properties on-the-fly with high statistical significances, enabling actual usage in clinical and biophysical studies.
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Research context

OpenAlex topics: Cellular Mechanics and Interactions · 3D Printing in Biomedical Research

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