Nanotoxicity: Mechanistic Investigation of the Biological Effects of SiO₂, TiO₂, and ZnO Nanoparticles on Intestinal Cells (Small 28/2015)

D. T. Leong and co-workers investigate the biological effects of several nanoparticles commonly found in food products. Using a panel of human colorectal cell lines, they reveal a complex interdependence between the physiochemical properties of the nanoparticles with the genetic landscape of the cells in effecting a cascade of inflammatory outcomes. On page 3458, this study underscores the important facets involved in understanding the nano-bio interaction of food-based nanomaterials in the gut for their subsequent applications.