Drug Delivery: Zn2+‐Triggered Drug Release from Biocompatible Zirconium MOFs Equipped with Supramolecular Gates (Small 31/2015)
Source abstract
Abstract
Encouraged by recent advances in materials science and nanomedicine, on page 3807 Y.-W. Yang and co-workers first applied benign activation mechanisms to targeted drug-release systems based on monodisperse, biofriendly zirconium nanoMOFs with pillarene-based stimuli-responsive supramolecular switches as nanovalves, aiming at targeted CNS disease therapy by combining physical (thermal heating) and natural biochemical treatments (Zn2+ ions, abundant in synaptic vesicles). This nanoscale-targeted smart drug-delivery system will prove to be a new generation of drug-delivery systems especially for CNS disease therapy in the near future.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Nanoplatforms for cancer theranostics · Advanced Nanomaterials in Catalysis · Supramolecular Self-Assembly in Materials
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Affiliations
State Key Laboratory of Inorganic Synthesis and Preparative Chemistry College of Chemistry International Joint Research Laboratory of Nano‐Micro Architecture Chemistry (NMAC) Jilin University 2699 Qianjin Street Changchun 130012 P. R. China
Key Laboratory of Cluster Science Ministry of Education of China School of Chemistry Beijing Institute of Technology 5 South Zhongguancun Street Beijing 100081 P. R. China
References
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