Nanomechanical Fingerprints of UV Damage To DNA
Source abstract
Abstract
Doing damage to DNA: The effects of UV radiation on the mechanics of individual DNA duplexes (see picture) are revealed by AFM-based spectroscopy. It is found that the width of the characteristic B–S plateau in the force spectrogram of irradiated DNA shortens in a UV-dose-dependent manner. These mechanical effects likely represent the local unwinding of the double helix caused by a massive formation of pyrimidine dimers and 6–4 lesions.
Source: openalex_inverted_index · Quality: baseline
Research context
OpenAlex topics: Force Microscopy Techniques and Applications · Mechanical and Optical Resonators · Ion-surface interactions and analysis
SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.
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