journal article·2024-08Open access

Injectable Self‐Oxygenating Cardio‐Protective and Tissue Adhesive Silk‐Based Hydrogel for Alleviating Ischemia After Mi Injury (Small 32/2024)

Shabir Hassan, Zahra Rezaei, Eder Luna, Dilara Yilmaz‐Aykut, Myung Chul Lee, Ana Marie Perea, Anurag Jamaiyar, Nicole Bassous, Minoru Hirano, Fatima Mumtaza Tourk, Cholong Choi, Malin Becker, Iman Yazdi, Kai Fan, Alan Eduardo Avila‐Ramirez, David Ge, Reza Abdi, Sudeshna Fisch, Jeroen Leijten, Mark W. Feinberg, Biman B. Mandal, Ronglih Liao, Su Ryon Shin

Small· Volume 20· Issue 32

Abstract

Silk-Based Hydrogels In article number 2312261, Su Ryon Shin and co-workers present that the local delivery of oxygen and a chemoattractant of stem cells via injectable, mechanically robust, and tissue-adhesive silk-based hybrid hydrogels alleviated ischemia and induced host stem cell homing at the myocardial infarction area, leading to decreased fibrotic scar formation and improved cardiac functional recovery.
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Research context

OpenAlex topics: Electrospun Nanofibers in Biomedical Applications · Tissue Engineering and Regenerative Medicine · Silk-based biomaterials and applications

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Affiliations

Division of Engineering in Medicine, Brigham and Women's Hospital, Department of Medicine Harvard Medical School 65 Landsdowne St Cambridge 02139 United States

Department of Biological Sciences Khalifa University Shakhbout Bin Sultan St Abu Dhabi 127788 United Arab Emirates

Biotechnology Center (BTC) Khalifa University Shakhbout Bin Sultan St Abu Dhabi 127788 United Arab Emirates

Department of Chemical Engineering Sharif University of Technology Tehran 1365‐11155 Iran

Department of Chemical Engineering Faculty of Engineering Istanbul University‐Cerrahpaşa Istanbul 34320 Turkey

Biomedical Research Division Medicinal Materials Research Center, Korea Institute of Science and Technology (KIST) Seoul South Korea

School of Science and Engineering, Technologico de Monterrey Monterrey Mexico

Division of Cardiovascular Medicine Department of Medicine Brigham and Women's Hospital, Harvard Medical School Boston MA 02115 USA

Future Vehicle Research Department Toyota Research Institute North America Toyota Motor North America, Inc. 1555 Woodridge Ave. Ann Arbor MI 48105 USA

Department of Mechanical Engineering Northeastern University Boston MA 02115 USA

Department of BioEngineering Technologies Faculty of Science and Technology Technical Medical Centre University of Twente Drienerlolaan 5 Enschede 7522 NB The Netherlands

School of Arts and Sciences Regis College 235 Wellesley Street Weston MA 02493 USA

School of Automation Hangzhou Dianzi Hangzhou Zhejiang 310018 China

Division of Biological and Environmental Science Engineering (BESE) King Abdullah University of Science and Technology (KAUST) Thuwal 23955‐6900 Saudi Arabia

Transplantation Research Center Renal Division Brigham and Women's Hospital / Harvard Medical School Boston MA 02115 USA

Department of Biosciences and Bioengineering Indian Institute of Technology Guwahati Guwahati Assam 781039 India

Center for nanotechnology Indian Institute of Technology Guwahati (IITG) Guwahati Assam 781039 India

Jyoti and Bhupat Mehta School of health Sciences and Technology, Indian Institute of Technology Guwahati (IITG) Guwahati Assam 781039 India

School of Medicine Stanford University Stanford CA 94305‐5101 USA

Stanford Amyloid Center Stanford University Stanford CA 94305‐5101 USA

References

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