DataVXSmallPaper
journal article·2022-05

3D Bioprinted GelMA‐Nanoclay Hydrogels Induce Colorectal Cancer Stem Cells Through Activating Wnt/β‐Catenin Signaling (Small 18/2022)

Yanmei Zhang, Zixuan Wang, Qifan Hu, Hao Luo, Bingchuan Lu, Yunhe Gao, Zhi Qiao, Yongsen Zhou, Yongcong Fang, Jin Gu, Ting Zhang, Zhuo Xiong

Small· Volume 18· Issue 18
Publisher page
Source abstract

Abstract

Cancer Stem Cells In article number 2200364, Zhuo Xiong and co-workers report that 3D bioprinted GelMA-nanoclay hybrid hydrogels can induce and enrich colorectal cancer stem cells (CSCs) by promoting the formation of spheroids by activating Wnt/β-catenin signaling. These spheroids can be isolated easily and are promising CSC enrichment models with increased stemness, high consistency, yield and efficiency for targeting CSC drug screening.
Source: openalex_inverted_index · Quality: baseline

Research context

PolymersNanomaterials

OpenAlex topics: Mesenchymal stem cell research

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Biomanufacturing Center Department of Mechanical Engineering Tsinghua University Beijing 100084 P. R. China

Biomanufacturing and Rapid Forming Technology Key Laboratory of Beijing Beijing 100084 P. R. China

Biomanufacturing and Engineering Living Systems Innovation International Talents Base (111 Base) Beijing 100084 P. R. China

MOE Key Laboratory of Bioinformatics BNRIST Bioinformatics Division Department of Automation Tsinghua University Beijing 100084 P. R. China

Senior Department of General Surgery the First Medical Center of Chinese PLA General Hospital Beijing 100853 P. R. China

References

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