journal article·2019-01

Nanoplumbing with 2D Metamaterials

Saroj Dangi, Robert Riehn

Small· Volume 15· Issue 2
Publisher page

Abstract

Abstract Complex manipulations of DNA in a nanofluidic device require channels with branches and junctions. However, the dynamic response of DNA in such nanofluidic networks is relatively unexplored. Here, the transport of DNA in a 2D metamaterial made by arrays of nanochannel junctions is investigated. The mechanism of transport is explained as Brownian motion through an energy landscape formed by the combination of the confinement free energy of DNA and the effective potential of hydrodynamic flow, which both can be tuned independently within the device. For the quantitative understanding of DNA transport, a dynamic mean‐field model of DNA at a nanochannel junction is proposed. It is shown that the dynamics of DNA in a nanofluidic device with branched channels and junctions is well described by the model.
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Research context

OpenAlex topics: Nanopore and Nanochannel Transport Studies · Microfluidic and Bio-sensing Technologies · Electrostatics and Colloid Interactions

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

NC State University Raleigh NC 27695‐8202 USA

Funding

National Science Foundation · National Institutes of Health · North Carolina State University

References (60)

Show source-provided references
1. 10.1063/1.43454010.1063/1.434540 ↗
2. Gennes P. G. · 1979
3. 10.1021/ma00242a01510.1021/ma00242a015 ↗
4. 10.1002/bip.1977.36016070510.1002/bip.1977.360160705 ↗
5. 10.1073/pnas.050291710210.1073/pnas.0502917102 ↗
6. 10.1103/PhysRevE.77.06090110.1103/PhysRevE.77.060901 ↗
7. 10.1021/ma201277e10.1021/ma201277e ↗
8. 10.1021/ma400674q10.1021/ma400674q ↗
9. 10.1103/PhysRevE.91.05060110.1103/PhysRevE.91.050601 ↗
10. 10.1021/nl803030e10.1021/nl803030e ↗
11. 10.1103/PhysRevE.90.06260210.1103/PhysRevE.90.062602 ↗
12. 10.1103/PhysRevLett.94.19610110.1103/PhysRevLett.94.196101 ↗
13. 10.1088/0034-4885/75/10/10660110.1088/0034-4885/75/10/106601 ↗
14. 10.1088/0957-4484/21/39/39550210.1088/0957-4484/21/39/395502 ↗
15. 10.1103/RevModPhys.82.290310.1103/RevModPhys.82.2903 ↗
16. 10.1371/journal.pone.005586410.1371/journal.pone.0055864 ↗
17. 10.1039/c2lc40504k10.1039/c2lc40504k ↗
18. 10.1093/nar/gkq67310.1093/nar/gkq673 ↗
19. 10.1073/pnas.050380910210.1073/pnas.0503809102 ↗
20. Frykholm K. · Nucleic Acids Res. · 2016 · 44 · 7219
21. 10.1063/1.488277510.1063/1.4882775 ↗
22. 10.1039/c1sm05298e10.1039/c1sm05298e ↗
23. 10.1016/j.cis.2015.12.00210.1016/j.cis.2015.12.002 ↗
24. 10.1103/PhysRevE.92.06270110.1103/PhysRevE.92.062701 ↗
25. 10.1039/c0lc00680g10.1039/c0lc00680g ↗
26. 10.1021/ma501687k10.1021/ma501687k ↗
27. 10.1063/1.240022710.1063/1.2400227 ↗
28. 10.1021/mz300323a10.1021/mz300323a ↗
29. 10.1063/1.487951510.1063/1.4879515 ↗
30. 10.1103/PhysRevLett.110.20810310.1103/PhysRevLett.110.208103 ↗
31. 10.1103/PhysRevLett.119.26810210.1103/PhysRevLett.119.268102 ↗
32. 10.1140/epjst/e2014-02326-410.1140/epjst/e2014-02326-4 ↗
33. 10.1021/acs.macromol.7b0246610.1021/acs.macromol.7b02466 ↗
34. 10.1063/1.367520710.1063/1.3675207 ↗
35. 10.1116/1.58174010.1116/1.581740 ↗
36. 10.1038/ncomms1424310.1038/ncomms14243 ↗
37. 10.1063/1.151511510.1063/1.1515115 ↗
38. 10.1529/biophysj.105.07473210.1529/biophysj.105.074732 ↗
39. 10.1103/PhysRevLett.95.26810110.1103/PhysRevLett.95.268101 ↗
40. 10.1103/PhysRevLett.113.26810410.1103/PhysRevLett.113.268104 ↗
41. 10.1021/acs.analchem.6b0314910.1021/acs.analchem.6b03149 ↗
42. 10.1039/c3sm51214b10.1039/c3sm51214b ↗
43. 10.1021/acs.nanolett.5b0247610.1021/acs.nanolett.5b02476 ↗
44. 10.1103/PhysRevLett.80.155210.1103/PhysRevLett.80.1552 ↗
45. 10.1073/pnas.96.24.1376210.1073/pnas.96.24.13762 ↗
46. 10.1126/science.288.5468.102610.1126/science.288.5468.1026 ↗
47. 10.1038/nnano.2006.20610.1038/nnano.2006.206 ↗
48. 10.1073/pnas.071239810510.1073/pnas.0712398105 ↗
49. 10.1039/B809370A10.1039/B809370A ↗
50. 10.1021/nn507350e10.1021/nn507350e ↗
51. 10.1021/nl061137b10.1021/nl061137b ↗
52. 10.1073/pnas.040384910110.1073/pnas.0403849101 ↗
53. 10.1021/ma00210a02510.1021/ma00210a025 ↗
54. 10.1021/ma500326w10.1021/ma500326w ↗
55. 10.1103/PhysRevE.76.01112310.1103/PhysRevE.76.011123 ↗
56. 10.1103/PhysRevLett.108.22810510.1103/PhysRevLett.108.228105 ↗
57. 10.1103/PhysRevLett.91.03810210.1103/PhysRevLett.91.038102 ↗
58. 10.1021/acs.macromol.5b0037710.1021/acs.macromol.5b00377 ↗
59. 10.1021/acs.macromol.7b0227010.1021/acs.macromol.7b02270 ↗
60. 10.1021/nl802256s10.1021/nl802256s ↗