DataVXSmallPaper
journal article·2022-07

Near Infrared‐Triggered Theranostic Nanoplatform with Controlled Release of HSP90 Inhibitor for Synergistic Mild Photothermal and Enhanced Nanocatalytic Therapy with Hypoxia Relief (Small 28/2022)

Boshi Tian, Chen Wang, Yaqian Du, Shuming Dong, Lili Feng, Bin Liu, Shikai Liu, He Ding, Shili Gai, Fei He, Piaoping Yang

Small· Volume 18· Issue 28
Publisher page
Source abstract

Abstract

Hypoxic Tumor Therapy In article number 2200786, Lili Feng, He Ding, Piaoping Yang, and co-workers develop a near-infrared (NIR)–triggered nanoplatform with controlled release of a heat shock proteins (HSPs) inhibitor for synergistic mild photothermal and enhanced Fenton nanocatalysis. Upon NIR irradiation, gambogic acid is released and inhibits the expression of HSP90. Notably, the nanoplatform simultaneously relieves the tumor hypoxia and enhances the efficacy of the nanocatalytic therapy in an acidic tumor microenvironment.
Source: openalex_inverted_index · Quality: baseline

Research context

Nanomaterials

OpenAlex topics: Nanoplatforms for cancer theranostics · Cancer, Hypoxia, and Metabolism · Heme Oxygenase-1 and Carbon Monoxide

SciVX discovery tags are terminology-based. OpenAlex topics are source-provided classifications.

Affiliations

Key Laboratory of Superlight Materials and Surface Technology Ministry of Education College of Materials Science and Chemical Engineering Harbin Engineering University Harbin 150001 P. R. China

The Key Laboratory of Rare Earth Functional Materials and Applications Zhoukou Normal University Zhoukou 466001 P. R. China

Department of Research Guangxi Medical University Cancer Hospital 71 Hedi Road Nanning 530021 P. R. China

Yantai Research Institute Harbin Engineering University Yantai 264000 P. R. China

References

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